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Conditional overexpression of transgenes in megakaryocytes and platelets in vivo

Megakaryocyte (MK)–specific transgene expression has proved valuable in studying thrombotic and hemostatic processes. Constitutive expression of genes, however, could result in altered phenotypes due to compensatory mechanisms or lethality. To circumvent these limitations, we used the tetracycline/d...

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Autori principali: Nguyen, Hao G., Yu, Guangyao, Makitalo, Maria, Yang, Dan, Xie, Hou-Xiang, Jones, Matthew R., Ravid, Katya
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895218/
https://ncbi.nlm.nih.gov/pubmed/15890684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0638
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