Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

It is well established that protein kinase C (PKC) isozymes play distinctive roles in mitogenic and survival signaling as well as in cancer progression. PKCε, the product of the PRKCE gene, is upregulated in various types of cancers including prostate, lung and breast cancer. To address a potential...

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Autores principales: Benavides, Fernando, Blando, Jorge, Perez, Carlos J, Garg, Rachana, Conti, Claudio J, DiGiovanni, John, Kazanietz, Marcelo G
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048798/
https://ncbi.nlm.nih.gov/pubmed/21224724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14469
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