Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

It is well established that protein kinase C (PKC) isozymes play distinctive roles in mitogenic and survival signaling as well as in cancer progression. PKCε, the product of the PRKCE gene, is upregulated in various types of cancers including prostate, lung and breast cancer. To address a potential...

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Bibliographic Details
Main Authors: Benavides, Fernando, Blando, Jorge, Perez, Carlos J, Garg, Rachana, Conti, Claudio J, DiGiovanni, John, Kazanietz, Marcelo G
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048798/
https://ncbi.nlm.nih.gov/pubmed/21224724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14469
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