COX-2 MEDIATES PRO-TUMORIGENIC EFFECTS OF PKCε IN PROSTATE CANCER

The pro-oncogenic kinase PKCε is overexpressed in human prostate cancer and cooperates with loss of the tumor suppressor Pten for the development of prostatic adenocarcinoma. However, the effectors driving PKCε-mediated phenotypes remain poorly defined. Here, using cellular and mouse models, we show...

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Publicado en:Oncogene
Main Authors: Garg, Rachana, Blando, Jorge M., Perez, Carlos J., Lal, Priti, Feldman, Michael D., Smyth, Emer M., Ricciotti, Emanuela, Grosser, Tilo, Benavides, Fernando, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195867/
https://ncbi.nlm.nih.gov/pubmed/29765153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0318-9
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