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Reduced Tumor Necrosis Factor-α and Transforming Growth Factor-β(1) Expression in the Lungs of Inbred Mice that Fail to Develop Fibroproliferative Lesions Consequent to Asbestos Exposure

Tumor necrosis factor (TNF)-α and transforming growth factor (TGF)-β mRNA and protein expression and the degree of fibroproliferative response to inhaled asbestos fibers are clearly reduced in the 129 inbred mouse strain as compared with typical fibrogenesis observed in the C57BL/6 inbred strain. Th...

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Autori principali: Brass, David M., Hoyle, Gary W., Poovey, Halet G., Liu, Jing-Yao, Brody, Arnold R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866420/
https://ncbi.nlm.nih.gov/pubmed/10079263
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