Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation

The mammalian translocon-associated protein (TRAP) complex comprises four transmembrane protein subunits in the endoplasmic reticulum. The complex associates with the Sec61 translocon, although its function in vivo remains unknown. Here, we show the involvement of the TRAP complex in endoplasmic ret...

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Hlavní autoři: Nagasawa, Koji, Higashi, Toshio, Hosokawa, Nobuko, Kaufman, Randal J, Nagata, Kazuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
Scientific Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866203/
https://ncbi.nlm.nih.gov/pubmed/17380188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400933
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