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A novel ER α-mannosidase-like protein accelerates ER-associated degradation

The quality control mechanism in the endoplasmic reticulum (ER) discriminates correctly folded proteins from misfolded polypeptides and determines their fate. Terminally misfolded proteins are retrotranslocated from the ER and degraded by cytoplasmic proteasomes, a mechanism known as ER-associated d...

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Detalhes bibliográficos
Main Authors: Hosokawa, Nobuko, Wada, Ikuo, Hasegawa, Kiyotaka, Yorihuzi, Tetuya, Tremblay, Linda O., Herscovics, Annette, Nagata, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083879/
https://ncbi.nlm.nih.gov/pubmed/11375934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve084
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