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A novel ER α-mannosidase-like protein accelerates ER-associated degradation
The quality control mechanism in the endoplasmic reticulum (ER) discriminates correctly folded proteins from misfolded polypeptides and determines their fate. Terminally misfolded proteins are retrotranslocated from the ER and degraded by cytoplasmic proteasomes, a mechanism known as ER-associated d...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083879/ https://ncbi.nlm.nih.gov/pubmed/11375934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve084 |
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