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Characterization of Schizosaccharomyces pombe ER α-Mannosidase: A Reevaluation of the Role of the Enzyme on ER-associated Degradation
It has been postulated that creation of Man(8)GlcNAc(2) isomer B (M8B) by endoplasmic reticulum (ER) α-mannosidase I constitutes a signal for driving irreparably misfolded glycoproteins to proteasomal degradation. Contrary to a previous report, we were able to detect in vivo (but not in vitro) an ex...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237077/ https://ncbi.nlm.nih.gov/pubmed/16079177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0246 |
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