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Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit
Most eukaryotic cells show a strong preference for the transfer in vivo and in vitro of the largest dolichol-P-P-linked glycan (Glc(3)Man(9)GlcNAc(2)) to protein chains over that of biosynthetic intermediates that lack the full complement of glucose units. The oligosaccharyltransferase (OST) is a mu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1595424/ https://ncbi.nlm.nih.gov/pubmed/17001015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607086103 |
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