Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation

The mammalian translocon-associated protein (TRAP) complex comprises four transmembrane protein subunits in the endoplasmic reticulum. The complex associates with the Sec61 translocon, although its function in vivo remains unknown. Here, we show the involvement of the TRAP complex in endoplasmic ret...

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Main Authors: Nagasawa, Koji, Higashi, Toshio, Hosokawa, Nobuko, Kaufman, Randal J, Nagata, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Scientific Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866203/
https://ncbi.nlm.nih.gov/pubmed/17380188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400933
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