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ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation–enhancing α-mannosidase–like protein 3 (EDEM3)
Protein folding in the cell is regulated by several quality-control mechanisms. Correct folding of glycoproteins in the endoplasmic reticulum (ER) is tightly monitored by the recognition of glycan signals by lectins in the ER-associated degradation (ERAD) pathway. In mammals, mannose trimming from N...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6036223/ https://ncbi.nlm.nih.gov/pubmed/29784879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003129 |
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