Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy

The membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of broadly neutralizing monoclonal antibodies (MAbs) 2F5, 4E10, and Z13. Here we engrafted the MPER into the V1/2 region of HIV-1 gp120 to investigate the ability of the engineered antigens t...

Full description

Saved in:
Bibliographic Details
Main Authors: Law, Mansun, Cardoso, Rosa M. F., Wilson, Ian A., Burton, Dennis R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866136/
https://ncbi.nlm.nih.gov/pubmed/17267498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02536-06
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items