Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

The identification and epitope mapping of broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies (Abs) is important for vaccine design, but, despite much effort, very few such Abs have been forthcoming. Only one broadly neutralizing anti-gp41 monoclonal Ab (MAb), 2F5, has b...

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Detalhes bibliográficos
Main Authors: Zwick, Michael B., Labrijn, Aran F., Wang, Meng, Spenlehauer, Catherine, Saphire, Erica Ollmann, Binley, James M., Moore, John P., Stiegler, Gabriela, Katinger, Hermann, Burton, Dennis R., Parren, Paul W. H. I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114669/
https://ncbi.nlm.nih.gov/pubmed/11602729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10892-10905.2001
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