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Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

The identification and epitope mapping of broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies (Abs) is important for vaccine design, but, despite much effort, very few such Abs have been forthcoming. Only one broadly neutralizing anti-gp41 monoclonal Ab (MAb), 2F5, has b...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Zwick, Michael B., Labrijn, Aran F., Wang, Meng, Spenlehauer, Catherine, Saphire, Erica Ollmann, Binley, James M., Moore, John P., Stiegler, Gabriela, Katinger, Hermann, Burton, Dennis R., Parren, Paul W. H. I.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.10892-10905.2001
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