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Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate
Polo-like kinase-1 (Plk1) phosphorylates a number of mitotic substrates, but the diversity of Plk1-dependent processes suggests the existence of additional targets. Plk1 contains a specialized phosphoserine–threonine binding domain, the Polo-box domain (PBD), postulated to target the kinase to its s...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1864981/ https://ncbi.nlm.nih.gov/pubmed/17446864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601683 |
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