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Phosphorylation- and Polo-Box–dependent Binding of Plk1 to Bub1 Is Required for the Kinetochore Localization of Plk1

Polo-like kinase 1 (Plk1) is required for the generation of the tension-sensing 3F3/2 kinetochore epitope and facilitates kinetochore localization of Mad2 and other spindle checkpoint proteins. Here, we investigate the mechanism by which Plk1 itself is recruited to kinetochores. We show that Plk1 bi...

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Autori principali: Qi, Wei, Tang, Zhanyun, Yu, Hongtao
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525235/
https://ncbi.nlm.nih.gov/pubmed/16760428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-03-0240
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