Essential Roles of the CC Chemokine Ligand 3-CC Chemokine Receptor 5 Axis in Bleomycin-Induced Pulmonary Fibrosis through Regulation of Macrophage and Fibrocyte Infiltration

We investigated the pathogenic roles of CC chemokine ligand (CCL)3 and its receptors, CC chemokine receptor (CCR)1 and CCR5, in bleomycin (BLM)-induced pulmonary fibrosis (PF). An intratracheal injection of BLM into wild-type (WT) mice caused a massive infiltration of granulocytes and macrophages, f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ishida, Yuko, Kimura, Akihiko, Kondo, Toshikazu, Hayashi, Takahito, Ueno, Masaya, Takakura, Nobuyuki, Matsushima, Kouji, Mukaida, Naofumi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2007
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864886/
https://ncbi.nlm.nih.gov/pubmed/17322370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.051213
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