Absence of IFN-γ accelerates thrombus resolution through enhanced MMP-9 and VEGF expression in mice

Deep vein thrombosis (DVT) is a major cause of pulmonary thromboembolism, a leading cause of death in individuals with DVT. Several lines of evidence indicate proinflammatory cytokines such as TNF-α are involved in thrombus formation and resolution, but the roles of IFN-γ remain unclear. To address...

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Hlavní autoři: Nosaka, Mizuho, Ishida, Yuko, Kimura, Akihiko, Kuninaka, Yumi, Inui, Masanori, Mukaida, Naofumi, Kondo, Toshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223815/
https://ncbi.nlm.nih.gov/pubmed/21646723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40782
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