Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes

After the ligation of the inferior vena cava (IVC) of wild-type (WT) mice, venous thrombi formed and grew progressively until 5 days and resolved thereafter. Concomitantly, intrathrombotic gene expression of Il6 was enhanced later than 5 days after IVC ligation. IL-6 protein expression was detected...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Nosaka, Mizuho, Ishida, Yuko, Kimura, Akihiko, Kuninaka, Yumi, Taruya, Akira, Ozaki, Mitsunori, Tanaka, Atushi, Mukaida, Naofumi, Kondo, Toshikazu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019028/
https://ncbi.nlm.nih.gov/pubmed/32117207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03150
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