Interferon-γ Plays Protective Roles in Sodium Arsenite-Induced Renal Injury by Up-Regulating Intrarenal Multidrug Resistance-Associated Protein 1 Expression

Subcutaneous injection of sodium arsenite (NaAs, 12.5 mg/kg) into BALB/c [wild-type (WT)] mice causes acute renal dysfunction characterized by severe hemorrhages, acute tubular necrosis, and cast formation, with increases in serum blood urea nitrogen and creatinine levels. Concomitant enhancement in...

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Detalhes bibliográficos
Main Authors: Kimura, Akihiko, Ishida, Yuko, Hayashi, Takahito, Wada, Takashi, Yokoyama, Hitoshi, Sugaya, Takeshi, Mukaida, Naofumi, Kondo, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780179/
https://ncbi.nlm.nih.gov/pubmed/17003472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060024
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