Laddar...

A Molecular Dynamics Study of the Ligand Release Path in Yeast Cytosine Deaminase

Yeast cytosine deaminase, a zinc metalloenzyme, catalyzes the deamination of cytosine to uracil. Experimental and computational evidence indicates that the rate-limiting step is product release, instead of the chemical reaction step. In this work, we use molecular dynamics to suggest ligand exit pat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yao, Lishan, Yan, Honggao, Cukier, Robert I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864842/
https://ncbi.nlm.nih.gov/pubmed/17218460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.098921
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!