Smad3 allostery links TGF-β receptor kinase activation to transcriptional control

Smad3 transduces the signals of TGF-βs, coupling transmembrane receptor kinase activation to transcriptional control. The membrane-associated molecule SARA (Smad Anchor for Receptor Activation) recruits Smad3 for phosphorylation by the receptor kinase. Upon phosphorylation, Smad3 dissociates from SA...

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Bibliographic Details

Published in:	Genes Dev
Main Authors:	Qin, Bin Y., Lam, Suvana S., Correia, John J., Lin, Kai
Format:	Artigo
Language:	Inglês
Published:	Cold Spring Harbor Laboratory Press 2002
Subjects:	Research Paper
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186427/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1002002
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