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Apoptosis in podocytes induced by TGF-β and Smad7

Primary and secondary forms of focal segmental glomerulosclerosis (FSGS) are characterized by depletion of podocytes and constitute a central manifestation of chronic progressive glomerular diseases. Here we report that podocytes undergo apoptosis at early stages in the course of progressive glomeru...

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Publicado no:J Clin Invest
Principais autores: Schiffer, Mario, Bitzer, Markus, Roberts, Ian S.D., Kopp, Jeffrey B., ten Dijke, Peter, Mundel, Peter, Böttinger, Erwin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11560950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12367
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