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The transcriptional co-activator P/CAF potentiates TGF-β/Smad signaling
Smads perform pivotal functions in the intracellular signaling of transforming growth factor-β (TGF-β). TGF-β-mediated activation of TGF-β type I receptor stimulates the phosphorylation of Smad2 and Smad3 and subsequent heteromeric complex formation with Smad4. The heteromeric Smad complexes translo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC113149/ https://ncbi.nlm.nih.gov/pubmed/11058129 |
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