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The transcriptional co-activator P/CAF potentiates TGF-β/Smad signaling

Smads perform pivotal functions in the intracellular signaling of transforming growth factor-β (TGF-β). TGF-β-mediated activation of TGF-β type I receptor stimulates the phosphorylation of Smad2 and Smad3 and subsequent heteromeric complex formation with Smad4. The heteromeric Smad complexes translo...

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Bibliografiske detaljer
Main Authors: Itoh, Susumu, Ericsson, Johan, Nishikawa, Jun-ichi, Heldin, Carl-Henrik, ten Dijke, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113149/
https://ncbi.nlm.nih.gov/pubmed/11058129
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