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Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

Inhibitory Smads, i.e. Smad6 and Smad7, are potent antagonists of the BMP–Smad pathway by interacting with activated bone morphogenetic protein (BMP) type I receptors and thereby preventing the activation of receptor-regulated Smads, or by competing with activated R-Smads for heteromeric complex for...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Itoh, Fumiko, Asao, Hironobu, Sugamura, Kazuo, Heldin, Carl-Henrik, ten Dijke, Peter, Itoh, Susumu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC149146/
https://ncbi.nlm.nih.gov/pubmed/11483516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4132
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