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Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

Inhibitory Smads, i.e. Smad6 and Smad7, are potent antagonists of the BMP–Smad pathway by interacting with activated bone morphogenetic protein (BMP) type I receptors and thereby preventing the activation of receptor-regulated Smads, or by competing with activated R-Smads for heteromeric complex for...

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Hlavní autoři: Itoh, Fumiko, Asao, Hironobu, Sugamura, Kazuo, Heldin, Carl-Henrik, ten Dijke, Peter, Itoh, Susumu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149146/
https://ncbi.nlm.nih.gov/pubmed/11483516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4132
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