Smad7 and protein phosphatase 1α are critical determinants in the duration of TGF-β/ALK1 signaling in endothelial cells
<p>Abstract</p> <p>Background</p> <p>In endothelial cells (EC), transforming growth factor-β (TGF-β) can bind to and transduce signals through ALK1 and ALK5. The TGF-β/ALK5 and TGF-β/ALK1 pathways have opposite effects on EC behaviour. Besides differential receptor binding, the duration of TGF-β sig...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BMC
2006-03-01
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| Serija: | BMC Cell Biology |
| Online dostop: | http://www.biomedcentral.com/1471-2121/7/16 |
| Oznake: |
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