Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

Inhibitory Smads, i.e. Smad6 and Smad7, are potent antagonists of the BMP–Smad pathway by interacting with activated bone morphogenetic protein (BMP) type I receptors and thereby preventing the activation of receptor-regulated Smads, or by competing with activated R-Smads for heteromeric complex for...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Itoh, Fumiko, Asao, Hironobu, Sugamura, Kazuo, Heldin, Carl-Henrik, ten Dijke, Peter, Itoh, Susumu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4132
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