The Bloom's syndrome gene product promotes branch migration of Holliday junctions

Bloom's syndrome (BS) is an autosomal recessive disorder associated with dwarfism, immunodeficiency, reduced fertility, and elevated levels of many types of cancer. BS cells show marked genomic instability; in particular, hyperrecombination between sister chromatids and homologous chromosomes. This...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Karow, Julia K., Constantinou, Angelos, Li, Ji-Liang, West, Stephen C., Hickson, Ian D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100448097
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