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The Bloom's syndrome gene product promotes branch migration of Holliday junctions

Bloom's syndrome (BS) is an autosomal recessive disorder associated with dwarfism, immunodeficiency, reduced fertility, and elevated levels of many types of cancer. BS cells show marked genomic instability; in particular, hyperrecombination between sister chromatids and homologous chromosomes....

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Detalhes bibliográficos
Main Authors: Karow, Julia K., Constantinou, Angelos, Li, Ji-Liang, West, Stephen C., Hickson, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18638/
https://ncbi.nlm.nih.gov/pubmed/10823897
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