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The Bloom's syndrome gene product promotes branch migration of Holliday junctions

Bloom's syndrome (BS) is an autosomal recessive disorder associated with dwarfism, immunodeficiency, reduced fertility, and elevated levels of many types of cancer. BS cells show marked genomic instability; in particular, hyperrecombination between sister chromatids and homologous chromosomes. This...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Karow, Julia K., Constantinou, Angelos, Li, Ji-Liang, West, Stephen C., Hickson, Ian D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100448097
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