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T7 endonuclease I resolves Holliday junctions formed in vitro by RecA protein.
T7 endonuclease I is known to bind and cleave four-way junctions in DNA. Since these junctions serve as analogues of Holliday junctions that arise during genetic recombination, we have investigated the action of T7 endonuclease I on recombination intermediates containing Holliday junctions. We find...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1990
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC332293/ https://ncbi.nlm.nih.gov/pubmed/2216756 |
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