The Bloom's syndrome gene product promotes branch migration of Holliday junctions

Bloom's syndrome (BS) is an autosomal recessive disorder associated with dwarfism, immunodeficiency, reduced fertility, and elevated levels of many types of cancer. BS cells show marked genomic instability; in particular, hyperrecombination between sister chromatids and homologous chromosomes....

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Bibliographic Details
Main Authors: Karow, Julia K., Constantinou, Angelos, Li, Ji-Liang, West, Stephen C., Hickson, Ian D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18638/
https://ncbi.nlm.nih.gov/pubmed/10823897
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