The Bloom's syndrome gene product promotes branch migration of Holliday junctions

Bloom's syndrome (BS) is an autosomal recessive disorder associated with dwarfism, immunodeficiency, reduced fertility, and elevated levels of many types of cancer. BS cells show marked genomic instability; in particular, hyperrecombination between sister chromatids and homologous chromosomes....

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Библиографические подробности
Главные авторы: Karow, Julia K., Constantinou, Angelos, Li, Ji-Liang, West, Stephen C., Hickson, Ian D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC18638/
https://ncbi.nlm.nih.gov/pubmed/10823897
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