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Endoplasmic reticulum chaperones inhibit the production of amyloid-β peptides
Aβ (amyloid-β peptides) generated by proteolysis of APP (β-amyloid precursor protein), play an important role in the pathogenesis of AD (Alzheimer's disease). ER (endoplasmic reticulum) chaperones, such as GRP78 (glucose-regulated protein 78), make a major contribution to protein quality contro...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1863563/ https://ncbi.nlm.nih.gov/pubmed/17132139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061318 |
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