The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation
The kinase activity of Abl is known to be regulated by a putative trans-acting inhibitor molecule interacting with the Src homology (SH) 3 domain of Abl. Here we report that the kinase-deficient Src (SrcKD) directly inhibits the tyrosine phosphorylation of Cbl and other cellular proteins by Abl. We...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2000
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10829062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060030697 |
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