The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

The kinase activity of Abl is known to be regulated by a putative trans-acting inhibitor molecule interacting with the Src homology (SH) 3 domain of Abl. Here we report that the kinase-deficient Src (SrcKD) directly inhibits the tyrosine phosphorylation of Cbl and other cellular proteins by Abl. We...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Shishido, Tomoyuki, Akagi, Tsuyoshi, Ouchi, Toru, Georgescu, Maria-Magdalena, Langdon, Wallace Y., Hanafusa, Hidesaburo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2000
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10829062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060030697
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!