The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

The kinase activity of Abl is known to be regulated by a putative trans-acting inhibitor molecule interacting with the Src homology (SH) 3 domain of Abl. Here we report that the kinase-deficient Src (SrcKD) directly inhibits the tyrosine phosphorylation of Cbl and other cellular proteins by Abl. We...

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書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Shishido, Tomoyuki, Akagi, Tsuyoshi, Ouchi, Toru, Georgescu, Maria-Magdalena, Langdon, Wallace Y., Hanafusa, Hidesaburo
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2000
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10829062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060030697
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