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Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

Nonhomologous end-joining (NHEJ) repairs DNA double-strand breaks created by ionizing radiation or V(D)J recombination of the immunoglobulin genes. The breaks often leave mismatched or nonligatable ends, and NHEJ must repair the breaks with high efficiency and minimal nucleotide loss. Here, the NHEJ...

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Detalhes bibliográficos
Main Authors: Tsai, Chun J., Kim, Sunny A., Chu, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859989/
https://ncbi.nlm.nih.gov/pubmed/17470781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702620104
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