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Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium

Vascular drug targeting may improve therapies, yet a thorough understanding of the factors that regulate effects of drugs directed to the endothelium is needed to translate this approach into the clinical domain. To define factors modulating the efficacy and effects of endothelial targeting, we used...

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Autores principales: Shuvaev, Vladimir V., Christofidou-Solomidou, Melpo, Scherpereel, Arnaud, Simone, Eric, Arguiri, Evguenia, Tliba, Samira, Pick, Jeremy, Kennel, Stephen, Albelda, Steven M., Muzykantov, Vladimir R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855632/
https://ncbi.nlm.nih.gov/pubmed/17270308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2006.12.025
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