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Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium

Vascular drug targeting may improve therapies, yet a thorough understanding of the factors that regulate effects of drugs directed to the endothelium is needed to translate this approach into the clinical domain. To define factors modulating the efficacy and effects of endothelial targeting, we used...

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Autors principals: Shuvaev, Vladimir V., Christofidou-Solomidou, Melpo, Scherpereel, Arnaud, Simone, Eric, Arguiri, Evguenia, Tliba, Samira, Pick, Jeremy, Kennel, Stephen, Albelda, Steven M., Muzykantov, Vladimir R.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855632/
https://ncbi.nlm.nih.gov/pubmed/17270308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2006.12.025
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