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Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors

Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of discovering new leads. In an attempt to tackle these issues, we have developed a process of virtual screenin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Jinn-Moon, Chen, Yan-Fu, Tu, Yu-Yin, Yen, Kuei-Rong, Yang, Yun-Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855430/
https://ncbi.nlm.nih.gov/pubmed/17502914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000428
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