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Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors

Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of discovering new leads. In an attempt to tackle these issues, we have developed a process of virtual screenin...

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Main Authors: Yang, Jinn-Moon, Chen, Yan-Fu, Tu, Yu-Yin, Yen, Kuei-Rong, Yang, Yun-Liang
格式: Artigo
語言:Inglês
出版: Public Library of Science 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855430/
https://ncbi.nlm.nih.gov/pubmed/17502914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000428
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