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Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors

Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of discovering new leads. In an attempt to tackle these issues, we have developed a process of virtual screenin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Jinn-Moon, Chen, Yan-Fu, Tu, Yu-Yin, Yen, Kuei-Rong, Yang, Yun-Liang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855430/
https://ncbi.nlm.nih.gov/pubmed/17502914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000428
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