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Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors

Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of discovering new leads. In an attempt to tackle these issues, we have developed a process of virtual screenin...

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Detalhes bibliográficos
Main Authors: Yang, Jinn-Moon, Chen, Yan-Fu, Tu, Yu-Yin, Yen, Kuei-Rong, Yang, Yun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855430/
https://ncbi.nlm.nih.gov/pubmed/17502914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000428
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