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The same genomic region conditions clonal deletion and clonal deviation to the CD8αα and regulatory T cell lineages in NOD versus C57BL/6 mice
Clonal deviation is a mechanism by which immature thymocytes expressing a self-reactive T cell antigen receptor (TCR) are rescued from clonal deletion by adopting an alternative differentiation pathway resistant to apoptosis. Here, we confirm and generalize previous indications that genetic alleles...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2007
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855402/ https://ncbi.nlm.nih.gov/pubmed/17438291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701777104 |
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