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The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors
FoxP3(+) regulatory T cells (Tregs) protect against autoimmunity, type 1 diabetes (T1D) in particular, prompting the hypothesis that a deficiency in Tregs is a critical determinant of diabetes susceptibility in NOD mice. However, tests of this hypothesis have yielded contradictory results. We confir...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604930/ https://ncbi.nlm.nih.gov/pubmed/19073938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810713105 |
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