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Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor–specified peripheral niche constraints

Treatment with anti-CD3 is a promising therapeutic approach for autoimmune diabetes, but its mechanism of action remains unclear. Foxp3(+) regulatory T (T reg) cells may be involved, but the evidence has been conflicting. We investigated this issue in mice derived from the NOD model, which were engi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nishio, Junko, Feuerer, Markus, Wong, Jamie, Mathis, Diane, Benoist, Christophe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931163/
https://ncbi.nlm.nih.gov/pubmed/20679403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100205
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