Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

Cellular DNA damage triggers the DNA damage response pathway and leads to enforcement of cell cycle checkpoints, which are essential for the maintenance of genomic integrity and are activated in early stages of tumorigenesis. A special feature of prostate cancer is its high incidence and multifocali...

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Autors principals: Kiviharju-af Hällström, Taija M., Jäämaa, Sari, Mönkkönen, Mia, Peltonen, Karita, Andersson, Leif C., Medema, René H., Peehl, Donna M., Laiho, Marikki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855358/
https://ncbi.nlm.nih.gov/pubmed/17431037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609299104
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