Differential epithelium DNA damage response to ATM and DNA-PK pathway inhibition in human prostate tissue culture

The ability of cells to respond and repair DNA damage is fundamental for the maintenance of genomic integrity. Ex vivo culturing of surgery-derived human tissues has provided a significant advancement to assess DNA damage response (DDR) in the context of normal cytoarchitecture in a non-proliferatin...

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Main Authors: Zhang, Zhewei, Yang, Zhiming, Jäämaa, Sari, Liu, Hester, Pellakuru, Laxmi G, Iwata, Tsuyoshi, af Hällström, Taija M, De Marzo, Angelo M, Laiho, Marikki
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356835/
https://ncbi.nlm.nih.gov/pubmed/22030624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.20.17841
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