The NHERF1 PDZ2 Domain Regulates PKA–RhoA–p38-mediated NHE1 Activation and Invasion in Breast Tumor Cells

Understanding the signal transduction systems governing invasion is fundamental for the design of therapeutic strategies against metastasis. Na(+)/H(+) exchanger regulatory factor (NHERF1) is a postsynaptic density 95/disc-large/zona occludens (PDZ) domain-containing protein that recruits membrane r...

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Auteurs principaux: Cardone, Rosa A., Bellizzi, Antonia, Busco, Giovanni, Weinman, Edward J., Dell'Aquila, Maria E., Casavola, Valeria, Azzariti, Amalia, Mangia, Anita, Paradiso, Angelo, Reshkin, Stephan J.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2007
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855021/
https://ncbi.nlm.nih.gov/pubmed/17332506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-07-0617
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